Kreatur — Mensch, Zauberer
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: Die Cuombajj-Hexen fügen einem Ziel deiner Wahl 1 Schadenspunkt und einem Ziel, das ein Gegner bestimmt, 1 Schadenspunkt zu.
You choose which opponent chooses the second target. It doesn't have to be the opponent who controls (or is) the first target.
Even though the opponent chooses a target, you control the ability. An opponent can't target a creature they control with hexproof.