Paying the alternative cost doesn’t change when you can cast the spell. A creature spell you cast this way, for example, can still only be cast during your main phase while the stack is empty.

You can’t exile a card from your hand to pay for itself. At the time you would pay costs, that card is on the stack, not in your hand.

If you don’t have two cards of the right color in your hand, you can’t choose to cast the spell using the alternative cost.

You may pay the alternative cost rather than the card’s mana cost. Any additional costs are paid as normal.